Preheat the oven to 375°F (190°C) and lightly grease a baking dish with cooking spray or olive oil.
In a large bowl, combine cottage cheese, broccoli, bell pepper, zucchini, cherry tomatoes, spinach, and red onion.
In a separate bowl, whisk eggs, olive oil, garlic powder, onion powder, black pepper, salt, and dried oregano.
Pour the egg mixture over the vegetables and stir gently until evenly coated.
Transfer the mixture to the prepared baking dish and spread evenly.
Sprinkle shredded mozzarella cheese over the top.
Bake uncovered for 30 to 35 minutes, or until the top is golden and the center is set.
Remove from oven and allow to cool slightly before serving.